Human studies at JEM: Immunology and beyond

Human studies at JEM: Immunology and beyond

The Rockefeller University Press $30.00 J. Exp. Med. 2016 Vol. 213 No. 4 467–468 www.jem.org/cgi/doi/10.1084/jem.20160211 467 Since its inception in 1896, The Journal of Experimental Medicine (JEM) has aimed to publish outstanding and enduring studies in medical biology, with an emphasis on pathogenesis (Welch, 1896). The founding editors and their successors have strived to provide a prestigio...

Developments at The JEM

1131 What does The Journal of Experimental Medicine look for in a paper? As the new Executive Editor of the Journal , I expect to be asked this question repeatedly. The Journal is known for its strengths in specific arenas, including immunology and inflammation, microbial pathogenesis, oncology, stem cell biology, hematopoiesis, as well as connective tissue and vascular biology. However, we wel...

The gut: beyond immunology.

The immune system is characterized by the ability to distinguish self from non-self. The intestinal immune system bears this latter property but, furthermore, it must discriminate among nutritious and beneficial substances from toxic or harmful ones. Considering that the gut has to be colonized by commensal bacteria participating in digestion as well as in the control of pathogen microorganisms...

Human tumor immunology at the molecular divide.

Research on human subjects in the JEM

A little more than a year ago, we published an editorial calling for papers describing research on human subjects (1). Research on human subjects is becoming more feasible because of advances in methodology, and investigations on human subjects are needed to advance the areas of human physiology and disease covered by the Journal. Patient-oriented research in particular is often perceived as be...